Studies on the typhoid chrome vaccine

Vaccine Treatment of Typhoid

the literature. Price, in the Lancet for December 1934, quotes the results of Uroiste of Montevideo and Stejskal of Vienna. These workers used carefully-standardized triple typhoid vaccine intravenously, to produce the shock. Triple vaccine, by virtue of its specificity, produces a more defined and uniform reaction than other foreign proteins or nonspecific vaccines. Being impressed by the succ...

A Note on Vaccine Therapy in Typhoid and Paratyphoid Fever

A conjugate vaccine against typhoid fever.

90 www.thelancet.com/infection Vol 14 February 2014 Zulfi qar Bhutta and colleages’ study in The Lancet Infectious Diseases marks an important milestone for the use of typhoid conjugate vaccines. Present Vi polysaccharide vaccines (Vi-PS) are not widely used because they cannot be given to children younger than 2 years and are thus excluded from the Expanded Programme of Immunization (EPI); fur...

Efficacy of purified Vi polysaccharide typhoid vaccine.

This experiment was conducted to assess the efficacy of typhoid vaccine newly produced by purifying Vi antigen of Salmonella typhi. With Karber method, LD50 of challenging organism (S. typhi ty2) was determined as 6.31 CFU/mouse, and then the organism was used for the study. With Probits method, ED50 of the vaccine was determined as 0.016 microg / 0.5 ml / mouse. The ELISA titer (0.5097+/-0.060...

Indian Vi conjugate typhoid vaccine: misleading claims.

447 VOLUME 47__MAY 17, 2010 I refer to the article “Vi conjugate Typhoid Vaccine” written by Garg SP(1) on behalf of the manufacturer of Peda TyphTM in response to my previous article on the same subject(2). The author states that “this novel vaccine has been found to be safe and effective in inducing very high levels of immune response (>90%) in infants, young children and adults”, and goes fu...